What kinds of treatments are we talking about?
Low-value medical practices are either ineffective or cost more than other options but only offer similar effectiveness.
“Medical reversals” are a subset of low-value medical practices. These practices are those that have been found, through randomized controlled trials, to be no better than a prior or lesser standard of care.*
Not only can low-value practices lead to physical and emotional patient harm, they can also lead to a distrust of the medical world and increased medical spending.
*Throughout this post, I cite several studies that compare treatments to a “lesser therapy” or “lesser standard of care”. These phrases are a bit ambiguous, but in general, these “lesser” options likely refer to a less expensive and simpler, possibly less toxic, treatment. Additionally, the term suggests that a prior therapy was at least as good as the newer therapy under investigation.
How common are ineffective and/or harmful treatments?
Researchers evaluated 3,000+ studies published between 2003-2017 in highly regarded medical journals. They found 396 routine medical practices that studies in leading journals clearly contradicted. In other words, they identified almost 400 practices that doctors consider conventional wisdom, even though there is no scientific proof of effectiveness.
And, another study examined the findings of 363 articles in a leading medical journal, each of which evaluated an existing medical practice. In these 363 articles, 40.2% found the existing practice to be no better than a lesser therapy, while only 38% reaffirmed that the existing practice was better than a lesser standard.
Certainly, these findings provide reasons to not blindly trust your doctor’s recommendations.
Another analysis on the value of treatments.
Additionally, researchers in another study analyzed randomized controlled trials on the harms and benefits of 3,000 medical treatments. The researchers rated the likeliness of benefits and harms for each treatment, with the following results:
- 11% – beneficial
- 23% – likely to be beneficial
- 7% – trade-offs between benefits and harms
- 6% – unlikely to be beneficial
- 3% – likely to be ineffective or harmful
- 50% – unknown effectiveness
Most noteworthy in these results, researchers found that approximately 1,500 treatments (50% of all reviewed) have an unknown effectiveness. This means no randomized controlled trials have shown the effectiveness, or ineffectiveness, of these 1,500 treatments!
We are all at risk.
However, since doctors we trust make these recommendations, and private and public insurers pay for these treatments, it’s easy for patients to feel comfortable with doctor recommendations.
Sometimes unproven treatments are the only choice.
Clearly, when we, or our loved ones, have a life-threatening or severely debilitating condition, we want a cure. But when there is no known cure, or when available treatments fail, unproven treatments can be a welcomed risk. So it’s not always a bad idea to choose an unproven treatment.
Examples of low-value or unproven practices.
Unproven treatments and medical advice commonly provided by doctors include:
- The use of magnesium oxide to ease nighttime leg cramps, even though research shows magnesium oxide and a placebo both led to a similar reduction in the number of nighttime leg cramps.
- Bed rest for pregnant women at risk for preterm births, even though research shows that bed rest doesn’t prevent preterm births, nor does it increase infant birth weight. On the contrary, studies show maternal bed rest leads to lower birth weight and lower gestational age at birth. Furthermore, research shows that pregnancy bed rest causes maternal health issues including muscle atrophy, weight loss and bone loss.
- The ketogenic (keto) diet for patients with obesity and type 2 diabetes, despite a lack of evidence about the potential benefits for those with these conditions.
A few examples in cardiac care.
Moreover, a large, well-designed study in 2005 showed that giving beta-blockers in the early hours of heart attacks didn’t save lives, but did cause a definite increase in dangerous heart failure.
Additionally, doctors routinely use of supplemental oxygen for patients with suspected heart attacks – even in patients with normal blood oxygen levels. However, research indicates this practice does not reduce mortality rates.
Furthermore, doctors frequently use stents (little mesh tubes) for patients with chest pain caused by narrowed or blocked arteries. Although the goal is to ease pain and reduce the risk of a heart attack in the future, studies show that stents don’t help patients live longer or reduce their risk of heart disease. Ironically, the actual procedure to insert a stent can lead to heart attacks and strokes. And it’s questionable if stents relieve chest pain.
A few examples in orthopedics.
Furthermore, these researchers strongly recommend against the procedure, even for patients who have imaging evidence of osteoarthritis, mechanical symptoms or a sudden onset of symptoms. Yet, globally this surgery is performed 2 million+ times a year. And in the US, these surgeries cost $3 billion every year.
Additionally, doctors routinely inject cement into broken vertebrae fractures, yet research shows the procedure does not relieve pain any better than a placebo. The researchers found that pain goes away or lessens within six weeks without the procedure.
Why do doctors recommend unproven or ineffective treatments?
So many reasons, including:
First, some doctors cannot break the habit of recommending treatments once considered standard care, even after randomized controlled trials find the practice ineffective or harmful. Unfortunately, it can take years, even decades, for the medical community to reverse its’ stance on conventional practices.
In other situations, doctors realize their recommendations are unproven or ineffective, but they are driven by profits. And sometimes doctors relent to the demands of patients who insist on particular treatments.
Finally, when there is no known cure or treatment, doctors may offer unproven treatments. In these cases, doctors should tell their patients that their recommendations are unproven for the patients’ conditions.
Importantly, even smart, experienced doctors can recommend outdated, low-value and/or unproven practices.
Can you trust your doctor’s recommendations? What should you do?
No one wants treatments that are ineffective, and certainly no one wants treatments that may cause harm. But should you blindly trust your doctor’s recommendations? What can you do to feel confident?
Research your options!
One noteworthy option, the website and app Choosing Wisely from the American Board of Internal Medicine, helps patients choose care that is 1) supported by evidence; 2) not duplicative of other tests or procedures already received; 3) free from harm; 4) truly necessary. Search by keyword to learn about medical practices that lack evidence, cause harm, or for which better approaches exist.
Additionally, you can reach out to patients with the same condition to learn about their experiences – other patients can be a great source of information (learn more in my blog post Can You Trust Advice from Other Patients?)
And ask your doctor(s) about less invasive options and the risks of a “wait and see” approach.
Get a second opinion.
Even if you trust your doctor’s recommendations, it’s always a good idea to get a 2nd, or even a 3rd, opinion. Don’t worry, you won’t insult your doctor. Actually, if your doctor urges you not to get a 2nd opinion, and your condition doesn’t require immediate attention, it might be time for a new doctor. For more information, read Why are Second Opinions Important?
More information.
You might find these posts helpful:
- The Dangers of Too Many Medical Tests and Treatments.
- 10 Tips to Communicate Better with Doctors.
- Help for Hard to Diagnose Health Issues.
- Can You Trust Medical Information Online?
- Should you Speak Up if You Think Your Doctor is Wrong? YES!
